Synthesis of Diphenyl Ether-4-acetic Acid
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چکیده
منابع مشابه
Synthesis and antitubercular activity of heterocycle substituted diphenyl ether derivatives.
Despite being an ancient disease, tuberculosis (TB) remains the leading single-agent infectious disease killer in the world. The emerging serious problem of TB control and clinical management prompted us to synthesize a novel series of heterocyclic substituted diphenyl ether derivatives and determine their activity against the H37Rv strain of Mycobacterium. All ten compounds inhibited the growt...
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In the crystal structure of the title mol-ecule, C(9)H(8)ClNO(3), adjacent mol-ecules are arranged into centrosymmetric dimers through pairs of inter-molecular O-H⋯O inter-actions. Inter-molecular N-H⋯O hydrogen bonds link the dimers into a layer parallel to the bc plane. In the layer, mol-ecules are packed in a face-to-face π-stacked arrangment, showing π-π stacking inter-actions between the b...
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The title compound, C(8)H(8)BrNO(4)S, a halogenated sulfon-amide, was prepared by basic hydrolysis of the methyl ester. In the crystal, mol-ecules form centrosymmetric hydrogen-bonded dimers via the carboxyl groups. These dimers are further linked by N-H⋯O inter-actions involving the carbonyl O and amide H atoms, forming a ribbon-like structure propagating in [010]. These ribbons are further li...
متن کامل(4-tert-Butylphenyl)acetic acid
In the title compound, C(12)H(16)O(2), the plane of the carboxylic acid group is almost perpendicular to the benzene ring [dihedral angle 80.9 (3)°] and the tert-butyl unit is disordered over two sets of sites in a 0.503 (6):0.497 (6) ratio. In the crystal structure, centrosymmetric dimers arise from pairs of O-H⋯O hydrogen bonds involving the carboxylic acid groups.
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1950
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.70.1_42